Enrichment analysis of differentially expressed genes between IPF and HC using REACTOME platform and Gene Set Enrichment Analysis (GSEA), showed that the most significantly enriched gene sets were “IFN signaling” and “IFNαβ signaling” (Figures 2A, B and Supplementary Tables 3A, B). Here, IFNA1 is linked to idiopathic pulmonary fibrosis.