Synaptic plasticity proteins were detected by western blot, Figure 5 shows that the expressions of PSD-95, GAP-43 and SYN in CUMS group [PSD-95: F(3, 8) = 5.54, p < 0.05; GAP-43: F(3, 8) = 11.84, p < 0.01; SYN: F(3, 8) = 8.60, p < 0.01] and MS+CUMS group [PSD-95: F(3, 8) = 5.54, p < 0.01; GAP-43: F(3, 8) = 11.84, p < 0.01; SYN: F(3, 8) = 8.60, p < 0.01] were downregulated. Here, DLG4 is linked to myeloid sarcoma.