TNF and psychotic disorder: Results showed that patients with first-episode psychosis and those with acute relapse of psychosis had significantly elevated levels of IL-1β, IL-6, TNF-α, IFN-γ, and IL-12, and patients under antipsychotic treatment showed a significant decline in IL-6, IL-1β, and IFN-γ and a rise in IL-12 and soluble IL-2 receptor.