For example, PCOS has previously been related to insulin receptor (INSR) gene with racial differences (Stewart et al., 2006; Wang et al., 2017a; Lin et al., 2019), and the family history might be a potential risk factor for the incidence of PCOS (Azziz and Kashar-Miller, 2000; Wang and Wang, 2017). Here, INSR is linked to polycystic ovary syndrome.