ACE2 and COVID-19: Upon infection with COVID-19, it binds to the host cell's angiotensin-converting enzyme 2 (ACE2) receptor, which commonly is found in cilia of glandular epithelium in the gastrointestinal tract and cholangiocytes (Hamming et al., 2004[16]), allows its entry into the target cell and facilitates replication (Xiao et al., 2020[39]).