PI3K/Akt, Wnt/β-catenin, ERK/MAPK, NF-κB, YY1, AP-1, JAK/STAT and CXCL12/CXCR4 signaling pathways have a significant function in the progression of cervical cancer in HPV infected individuals (Figure 2(Fig. 2)). The gene discussed is CXCL12; the disease is cervical cancer.