MYCN and bone metastasis: In our study, there were significant differences in bone metastasis, NSE, LDH, MTV and TLG between patients with progression and those without; age, sex, MYCN amplification, GD2 expression, tumor location, lymph node metastasis, other distant metastasis, bone marrow involvement, risk stratification and SUVmax showed no significant differences between the two groups (Table 1).