Patients with AKI presented lower birth weight, higher duration of symptoms before admission, duration of oxygen therapy, serum urea levels, CRP levels, and length of stay such as higher prevalence of preterm birth, signs of respiratory distress, RR > 2 SDS, need of oxygen therapy, need of high flow oxygen therapy, need of intubation, presence of fever, refill > 2 s, severe pneumonia, need of bolus, and hematocrit < 2 SDS, compared with patients without AKI (Table 1). This evidence concerns the gene CRP and acute kidney injury.