In osteosarcoma, SNHG4 expression was remarkably elevated, and high SNHG4 expression was correlated with larger tumor size and impaired prognosis of osteosarcoma patients; regarding the molecular mechanism, SNHG4 exerted oncogenic effects in osteosarcoma by sponging miR-224-3p [19]. This evidence concerns the gene SNHG4 and neoplasm.