SNHG4 and colorectal carcinoma: As further evidence, according to TCGA-CRC data, SNHG4 expression was dramatically increased in CRC M1-stage (lymphatic or distal metastatic) tissue samples compared with CRC M0-stage (nonmetastatic) tissue samples (Figure 1B) and was markedly enhanced in CRC microsatellite stable (MSS) tissue samples compared with CRC microsatellite instability (MSI) tissue samples (Figure 1C).