Three treatments in all asthma (Co-Q10: 903.4 ± 32.1; Co-Q10, O-3: 713.2 ± 24.3; and Co-Q10, Mg-s: 789.4 ± 43.6 ng/ml) and rhinitis (Co-Q10: 883.5 ± 19.4; Co-Q10, O-3: 748.3 ± 34.6; and Co-Q10, Mg-s: 783.5 ± 40.0) groups reduced significantly total IgE level in serum in compared with non-treated groups (Fig. 5). Here, IGHE is linked to asthma.