In the three treated groups of asthma and also, allergic rhinitis (Co-Q10 received groups, Co-Q10 and O-3 received groups, Co-Q10 and Mg-S received groups), reverse trend was found and significantly reduced IL-4, IL-5, IL-13, and restored the IFN-γ levels (P < 0.05) (Fig. 3). The gene discussed is IL4; the disease is allergic rhinitis.