CBFA2T3 and acute megakaryoblastic leukemia: CBFA2T3 participates in oncogenic recurrent translocations in acute myeloid leukemia (with the t(16;21)(q24;q22) giving rise to RUNX1-CBFA2T3) or acute megakaryoblastic leukemia (with inv [16] (p13q24) giving rise to CBFA2T3-GLIS2) [17].