Liu et al. showed overexpression of KIAA0101 tv1 at both mRNA and protein levels in ~ 70% of HCC tissues (~ 40% in stage I-II, and ~ 80% in stage III-IV HCCs) as assessed by semiquantitative RT-PCR, virtual northern blot, western blot, and IHC analysis [19]. Here, PCLAF is linked to hepatocellular carcinoma.