CCND1 and mantle cell lymphoma: Overall, current standard PCR techniques allow the identification of a molecular marker in 75%–80% of MCL patients, namely 65%–70% carrying an IGH clonal rearrangement and up to 30%–35% an amplifiable BCL1/IGH rearrangement (with a breakpoint located in the major translocation cluster [MTC] region ).10, 11