The pathways involved in common DEGs are shown in Figure 2C and D, including ptr04151 (PI3 K‐Akt signaling pathway), ptr05200 (Pathways in cancer), ptr04115 (p53 signaling pathway), ptr04015 (Rap1 signaling pathway), ptr04110(Cell cycle), ptr00250 (Alanine, aspartate and glutamate metabolism), ptr05218 (Melanoma), and ptr01230 (Biosynthesis of amino acids). The gene discussed is TP53; the disease is melanoma.