Rearrangements involving HMGA2 at chromosomal region 12q14.3 have been detected in a variety of benign mesenchymal and mixed tumors including lipomas and osteochondrolipomas, chondromas of soft tissue, uterine leiomyomas, salivary gland pleomorphic adenomas, and many other entities [31, 32]. This evidence concerns the gene HMGA2 and chondroma.