ABCA1 and neoplasm: Analysis of resected tumors indicated significantly increased expression of both canonical Abca1 (p < 0.001) and Abcb1b (the mouse gene for Pgp) (p < 0.0001) in GW3965 treated animals compared to controls (Fig. 3B), demonstrating that the LXR agonist had effectively activated relevant target genes within the tumor tissue.