Densities of all immune cell subtypes negatively correlated with the percentage of tumour area in the sample (CD3+ = −0.209, P = 0.028; CD8+ = −0.205, P = 0.031; CD4+ = −0.184, P = 0.053, Foxp3+ = −0.203, P = 0.033, Supplementary Fig. 8a). This evidence concerns the gene CD4 and neoplasm.