IFNG and acute respiratory distress syndrome: This data is paradoxical to a previous report where LPS-induced elevation of serum CXCL9 and CXCL10 was reported in an LPS-induced ARDS model38; however, neutralization of IFN-γ showed a marked decrease of plasma CXCL9 and CXCL10 levels39, suggesting a relationship between stable IFN-γ levels and reduced levels of CXCL9 or CXCL10 in OT2D.