SMIPP-Cs (transcript ranked 104th) (molecular weight: 36.48 kDa) was the closest homolog to the group 1 allergens of house dust mites (HDMs) (Table 2), which are proteolytic papain-like cysteine proteases that promote pathogenicity in asthma and allergy22 (Supplementary Figure 2). The gene discussed is CTSB; the disease is asthma.