Moreover, in reovirus-treated mice there was a significant negative correlation between the percentage of CD8+ TEM cells in the spleen and the percentage of CD138+ tumor cells in the BM (figure 2F; p=0.023, Pearson’s r=−0.62), suggesting a potential role for adaptive T cell antitumor immunity for the eradication of MM cells. Here, CD8A is linked to neoplasm.