Typical IHC staining images of tissues from patients with different prognoses are shown in Figure 6A. High expression of CHST4, SLC22A8, and STC2 predicted shorter time-to-relapse (TTR) and overall survival (OS) in patients with HCC (Figure 6B; P < 0.05). This evidence concerns the gene SLC22A8 and hepatocellular carcinoma.