The top 20 significant KEGG pathways are shown in Figure 3B. The DEGs were significantly enriched in NF-κB signaling pathway, cell adhesion molecules signaling pathway, and cytokine–cytokine receptor interaction signaling pathway, which suggested the differential expression of genes in these pathways may contribute to the aberrant activation and function of CD14+ monocytes in CAD patients were closely related to CAD process. Here, NFKB1 is linked to coronary artery disorder.