NPC1 and acute lymphoblastic leukemia: Other treatments did not significantly improve Purkinje cell survival in any cerebellar lobules (Npc1−/− ALL lobules I–II P = 0.107, lobule III P = 0.157, lobules IV–V P = 0.533; Npc1−/− ADL lobules I–II P = 0.60, lobule III P = 0.11, lobules IV–V P = 0.766, compared to Npc1−/− UT) (Fig. 2G and H).