However, ADLL and ALL treatment significantly lowered levels of specific GSLs including GA2 (ADLL: 21.3%, P = 0.0102; ALL: 23.8%, P = 0.0042), whereas a significant reduction in GA1 was only observed with ALL treatment (23.5%, P = 0.0254) (Fig. 2D). The gene discussed is ETFA; the disease is acute lymphoblastic leukemia.