SEMA6B and cancer: Accumulating evidence continues to emphasize the importance of various miRNAs in GBC with studies highlighting their relationship with the malignant behaviors displayed by cancer cells and correlation to poor oncologic outcomes of patients with GBC.15, 16, 17 The present study set out to elucidate the role of the functional miRNA cluster in connection with miR-30b/-30d in GBC via SEMA6B targeting.