Echocardiography revealed that compared with control group, left ventricle ejection fraction (LVEF) and fraction shorting (LVFS) were robustly reduced on 1 day post-Ml in the Ml group, YMSC group, AMSC group, and Apelin-AMSC group, indicating that the MI mouse model was successfully established (Supplementary Figure 4). The gene discussed is APLN; the disease is myocardial infarction.