Some studies report a decreased expression of the adhesion molecule E-cadherin on melanocytes, while another reported no significant differences in expression of adhesion molecules between healthy, nonlesional, and lesional skin but elevated expression of an “anti-adhesion molecule” tenascin in vitiligo lesional and nonlesional skin, which might lead to the loss of melanocytes within the skin (50, 51). This evidence concerns the gene CDH1 and vitiligo.