After adjustment for age, sex, thyroid hormone, TSH, thyroid autoimmunity, BMI, SBP, FPG, ALT, and eGFR at baseline, the results were similar (Table 4, Figure 3): the total effect of statin use on log-transformed TSH levels at the end of follow-up is significant (path c, βTol = -0.061, p = 0.002). This evidence concerns the gene TG and autoimmune thyroid disease.