PRRT2 and infection: As in Ae. aegypti, the An. stephensi PKC activation was also linked to the decrease of midgut epithelial barrier, resulting in the greater development of P. falciparum oocysts (Pakpour et al., 2013b), without modulation of NF-κB-dependent immune factors, thus indicating that the regeneration of the midgut epithelium is essential for infection control, as also suggested by Taracena et al. (2018).