Likewise, the expansion of inflammatory-oriented microglial clusters marked by increased intensity of IBA1, HLA-DR, and CD68 immunoreactivity and increased density of microglial nodules found in post-mortem brains of COVID-19 patients would be in line with this ongoing microgliosis (Mukandala et al., 2016; Matschke et al., 2020). This evidence concerns the gene AIF1 and COVID-19.