CXCL8 and COVID-19: In parallel, a recent report showed enhanced TREM2 protein levels in the CSF of a patient with COVID-19-associated encephalopathy, along with increased protein levels of IL6, IL8, and TNF in both CSF and serum (see section “Microglia Respond to the Systemic Inflammatory Response in COVID-19”) (Pilotto et al., 2020b).