SLC6A3 and Parkinson disease: In addition to PD-like motor symptoms such as postural instability and slowness of movement, and loss of DAT binding in the striatum, these patients show neurodevelopmental delays, epilepsy, pyramidal signs, and intellectual disabilities (Edvardson et al., 2012; Koroglu et al., 2013; Olgiati et al., 2016; Ng et al., 2020).