We also observed that the expression levels of Rab5a, Ephb1, Camk2a, Camk2d, Nefl, Tkfc, Fyn, Flot1, and Vdac1 were significantly down-regulated while Pak1, Cbr1, Dpysl2, Klc4, Klc2, Snx6, and Cttn were up-regulated in both the anxiety-susceptible and insusceptible groups compared with the control group. The gene discussed is KLC4; the disease is Anxiety.