The following HRs and p-values were obtained (without correction for residual tumor with 2 cm cut-off): CD8 TILs primary tumor: HR 0.57, p = 0.0519; PD-1 TILs metastases: HR 0.47, p = 0.0133; PD-L1 TILs metastases: HR 3.47, p = 0.0160; and combined as consecutive factor as above: HR 0.59, p = 0.0023. This evidence concerns the gene CD274 and neoplasm.