In addition, we have previously demonstrated that a peptide mimic of the KIR region of SOCS1 (SOCS1-KIR) prolonged the survival of SOCS1−/− mice, ameliorated pathology in a rodent model of multiple sclerosis, and mitigated experimental rodent uveitis12,14,28,29. The gene discussed is SOCS1; the disease is multiple sclerosis.