Among the dementia genes, we identified 3 likely pathogenic variants in GRN in 3 sporadic cases (p.C105Y, p.C389fs, p.C139R), one C9orf72 expansion in one sporadic case, 2 CSF1R mutations in the TK flanking regions and one loss of function mutation in SORL1 (p.R744X) in 2/3 affected members of Family H. Additionally, we detected a novel putative LoF mutation in a NCL gene, CLCN6 p.S116P, segregating with FTD with memory onset and PPA in Family E (Table 2). Here, GRN is linked to primary progressive aphasia.