For the unique positive interactions, where introduction of btn1102–208del into cells deleted for another gene causes cells to grow better, these genes are also linked to eye disorders (gfh1, hnt3) as well as lysosomal disorders (npc2, SPBC713.07c, SPBC1683.12), monogenic diseases (hri2, kms1, cds1), neurological (hhp2, SPCC1827.07c), and inborn mitochondrial metabolomic (cyt1, fsf1, SPBC8D2.18c) disorders. Here, NPC2 is linked to lysosomal storage disease.