In our study, we however observed that co-treatment with Dasatinib, a specific inhibitor of SRC phosphorylation, did not increase in vitro the effect mediated by NVP-BEP800 on the viability of cell lines, as well as on T-ALL or B-ALL cells isolated ex vivo from PDX mice (Supplementary Fig. S16). Here, SRC is linked to acute lymphoblastic leukemia.