MMP14 and rheumatoid arthritis: On the other hand, MSC-derived miR-150-5p exosomes (Exo-150) could suppress the migration of fibroblast-like synoviocytes (FLS), which play a crucial role in RA pathogenesis, and diminish tube formation in human umbilical vein endothelial cells (HUVECs) through targeting matrix metalloproteinase 14 (MMP14) and vascular endothelial growth factor (VEGF) in vitro [175].