Also, the frequency of Th1 and plasma cells in the spleen dwindled in transplanted groups in the absence of any moderation in Th2, Th17, Tfh, and Treg cell percentages and IL-6, IL-10, IL-17, and MCP-1 serum levels, suggesting that DP-derived stem cells can restore renal glomerular defects and perivascular inflammation and may be recruited as alternative sources for SLE treatment [92]. This evidence concerns the gene IL6 and systemic lupus erythematosus.