ICU patients with COVID-19 have exposed higher plasma levels of the inflammatory mediators, including IL-2, IL-6, and TNF-α, granulocyte colony-stimulating factor (GCSF), CCL2, macrophage inflammatory protein 1-α (MIP-1α), and interferon-gamma inducible protein 10 kDa (IP-10) [159]. This evidence concerns the gene CXCL10 and COVID-19.