GRHL2 and hepatocellular carcinoma: In case–control study, we identified one novel locus (SNP: rs1264473, Gene: GRHL2, P = 1.57 × 10–6) significantly associated with CHB, two novel loci (SNP: rs2833856, Gene: EVA1C, P = 1.62 × 10–6; SNP: rs4661093, Gene: ETV3, P = 2.26 × 10–6) significantly associated with HCC.