PCNA and pachyonychia congenita: Finally, Western Blot results showed that, compared to the control group, the expression of PCNA, c-caspase-3 and c-caspase-12 in PC tumor tissues in LV-FTX group were remarkably up-regulated (Fig. 6e, P < 0.05), indicating that silencing of FTX promoted the apoptosis of PC cells and decreased cell proliferation.