In addition, the expression levels of miR-513b-5p in PANC-1 and SW1990 cells of LV-FTX groups were significantly higher than that in the control group (Fig. 5b, P < 0.05), suggesting that silencing of FTX remarkably increased the expression levels of miR-513b-5p in PC cells. The gene discussed is FTX; the disease is pachyonychia congenita.