ADGRG6 and adolescent idiopathic scoliosis: Noncoding variants at the human ADGRG6 locus are associated with different aspects of musculoskeletal development, including height (Soranzo et al., 2009; J. Zhao et al., 2010) and adolescent idiopathic scoliosis (AIS) (Karner et al., 2015; Kou et al., 2013, 2018; Qin et al., 2017; J. F. Xu et al., 2015).