Myositis antibodies to any of the following antigens were found in 45/224 (20%) patients included in the assay: PL-7, SSA/Ro52, Mi-2 alpha, Mi-2beta, PM-cl75, PM-Scl100, Jo-1, Ku, PM-Scl75, SRP, TIF1gamma, SAE1, SAE1/SUMO1, Mi2, PL12. The gene discussed is SUMO1; the disease is myositis disease.