Interestingly, expression of some XAF1 transcripts was a negative prognostic factor in several cancer types, such as kidney renal clear cell carcinoma (KIRC), low‐grade glioma (LGG), and pancreatic adenocarcinoma (PAAD), while in melanoma (SKCM), all the transcripts were associated with a favorable outcome. The gene discussed is XAF1; the disease is melanoma.