Next, we evaluated the cytotoxicity of IL‐2‐stimulated NK cells against HNSCC, CAL27 and SCC‐25 cells, and found that the cytotoxicity of IL‐2‐stimulated NK cells against HNSCC cells was significantly enhanced by oe‐CXCL14, but was reduced by sh‐CXCL14 (Figure 2F,G). The gene discussed is CXCL14; the disease is head and neck squamous cell carcinoma.