Most ACC tumors show activation of MYB through gene fusion of MYB with the transcription factor NFIB due to a 6;9 translocation (Persson et al., 2009; Andersson and Stenman, 2016) or, less often, by truncation or copy number gain (Persson et al., 2012). Here, NFIB is linked to adrenal cortex carcinoma.