In previous work, we investigated the role of an acute increase in serum-free fatty acids levels observed in patients with Weil's disease, which can be represented mainly through OA/A and (OA + Linoleic/A) molar ratios and the serum albumin capacity to prevent in vitro NEUFA cytotoxic effects (Burth et al., 2005). The gene discussed is ALB; the disease is Weil's disease.