A number of lncRNAs, such as maternally expressed 3 (Meg3), myosin heavy-chain-associated RNA transcripts (Mhrt), cardiac hypertrophy-related factor (Chrf), Myocardial Infarction–Associated Transcript (Miat) have been reported to be involved in cardiac hypertrophy (24–27). The gene discussed is MEG3; the disease is cardiac hypertrophy.