Here we found that all of these three lncRNAs significantly associated with EZH2; however, whereas Malat1-EZH2 interaction was transiently enhanced after AngII treatment, Gm20417-EZH2 interaction was transiently suppressed and Gm37376-EZH2 interaction was constantly enhanced (Figures 6A–D), suggesting a complex regulation of EZH2 function in AngII-induced cardiac hypertrophy. This evidence concerns the gene EZH2 and cardiac hypertrophy.