IL-18 enhanced the expression of intercellular adhesion molecule-1 (ICAM-1) in human myelomonocytic cell lines (66), and ICAM-1 and vascular cell adhesion molecule-1 (VCAM-1) in endothelial cells and rheumatoid arthritis synovial fibroblasts (67). The gene discussed is VCAM1; the disease is rheumatoid arthritis.