QPCR further confirmed that organoids expressed latent EBV genes (Figure 1D), as well as displayed distinct cell borders [integrin and epithelial cell-adhesion molecule (EpCAM) staining] and cytoplasmic keratinization (pan-cytokeratin staining), which are histologic characteristics of squamous cell carcinoma (Figure 1E). The gene discussed is EPCAM; the disease is squamous cell carcinoma.