PAFAH1B3 and cancer: We first evaluated PAFAH1B3 expression in TCGA and GTEx pan-cancer database, and found higher PAFAH1B3 expression in 24 tumors compared with the corresponding normal tissues, including: ACC, BLCA, BRCA, CESC, CHOL, COAD, ESCA, GBM, HNSC, KIRP, LGG, LIHC, LUAD, LUSC, OV, PAAD, PRAD, READ, SCKM, STAD, TGCT, THCA, UCEC, and UCS (Figure 1A).