Crosstalk of keratinocytes and immune cells including DCs, T cells, mast cells, and neutrophils plays an important role in the pathogenesis of psoriasis, Cytokine-cytokine receptor pathway transmits intercellular interactions, with IL-23/IL-17 pathway currently being the most investigated (Chiricozzi et al., 2018). This evidence concerns the gene IL17A and psoriasis.